Applied Biosystems™ Axiom™ Genome-Wide EAS 1 Array Plate
On demandApplied Biosystems™ Axiom™ Genome-Wide EAS 1 Array Plate
Axiom World Arrays are designed for genome-wide imputation analysis with a focus in disease-associated genes. The arrays include additional markers that are specific to multiple HapMap populations. These arrays have the industry's highest coverage of rare variants to replicate studies of specific loci and/or genes that have been identified in previous genome-wide association studies. The use of imputation enables a highly cost-effective, budget conscious alternative to other commercially available arrays.
The Axiom Genome-Wide EAS 1 Array Plate is designed for maximum coverage of Admixed population and diseases of East Asian ancestry using intelligent pair-wise and imputation design tools.
Features
- Saturated coverage in over 5,000 gene regions previously identified as disease-associated: SNPs selected from disease and drug response GWAS databases including the National Human Genome Research Institute (NHGRI) Catalog of Published Associations, the Human Genome Epidemiology Navigator (HuGE), the Pharmacogenetics Knowledge Base (PharmaGKB), and the Pharmacogenetics Membrane Transporter (PMT) database
- Common and rare (MAF ∼1%) SNPs and indels from the International HapMap Project and 1000 Genomes Project
- Intelligent, innovative SNP selection maximizes efficient imputation of millions of additional SNPs
- GWAS, replication and fine mapping in one experiment to save time and cost
- Genotype-tested genomic content proven to give informative and reliable results
- High sample pass rate, call rate, and reproducibility
- Compatible with the Axiom 2.0 Reagent Kit, GeneTitan™ MC Instrument, automated or manual workflow, and Axiom Analysis Suite
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