Applied Biosystems™ PharmacoScan™ Assay Kit, 24-Format

Applied Biosystems™ PharmacoScan™ Assay Kit, 24-Format

Each PharmacoScan™ Assay Kit includes all necessary array plates, reagents, controls, and consumables to process 88 samples (and 8 controls) with the PharmacoScan Solution workflow.

PharmacoScan Solution is an ideal platform for translational researchers in healthcare, pharma, and research organizations looking to understand how genetic variations affect drug absorption, distribution, metabolism, and excretion (ADME).

By pre-emptively screening for risk factors on a microarray, users in research can precisely and reproducibly analyze 4,627 high- to low-evidence markers* within nearly 1,200 genes* in a single assay. The solution includes copy number variation calling and interrogating predictive markers in complex genes. Unlike solutions that analyze only high-evidence markers, PharmacoScan Solution presents a more comprehensive view for genotyping for pharmacogenomic risk.

Features

• 4,627 markers in 1,191 genes of known pharmacogenomic value
• Comprehensive content of known pharmacogenomic value including Phase I and Phase II enzymes, regulatory/modifier genes, drug target genes, and Phase III/transporter genes
• Comprehensive content of known pharmacogenomic value including Phase I and Phase II enzymes, regulatory/modifier genes, drug target genes, and Phase III/transporter genes
• Genotyping of highly predictive markers in genes including GSTM1, CYP1A2, CYP2D6, CYP2B6, CYP2A6, SULT1A1, CYP2C19, and CYP2C9 that are in highly homologous regions
• Copy number variation (CNV) analysis for copy number states ranging from zero to three-plus for important ADME genes
• Star allele and translation for key genes

Contents

• 24-format array plates, 4 Plates
• Reagent Kit (Includes reagents and controls for 4x24-format array plates)
• Gene Titan instrument consumables for 4x24-format array plates