Applied Biosystems™ TaqMan™ Array, Human TGFB Pathway, Fast 96-well

Applied Biosystems™ TaqMan™ Array, Human TGFB Pathway, Fast 96-well

These 96-well plates are pre-configured with the most appropriate TaqMan® Gene Expression Assays for a specific biological process, pathway, or disease state. Each plate contains predefined assays and endogenous controls dried-down in the wells, ready for accurate assessment of an entire gene signature in one simple experiment. The panel of assays in the TaqMan® Array 96-well Human TGFB Pathway Plate targets genes encoding members of the TGF-Beta superfamily of ligands: 1) TGFB family (TGF- B1, B2, B3); 2) Bone morphogenetic proteins (BMPs); 3) Growth and differentiation factors (GDFs); and 4) Others that include Anti-müllerian hormone (AMH), Activin A&B⁄Inihibin A&B, and Nodal. The TGF Beta receptors in the panel include Activin Type 1 and Type II Receptors, BMPRs, and TGFBR 1, 2 and 3. Members of the SMAD family are also present on the panel as they are central to the canonical TFGB signal transduction pathway. Additional genes in the panel are involved in regulating TGFB signaling as well as functions regulated by TGFBs.

Internal Probe Modification: MGB (Minor Groove Binder) (3'), Non-Fluorescent Quencher (3'), FAM (5')

Contents

• Each TaqMan™ Array Plate well contains a single TaqMan™ Assay for one 10 µL reaction