Applied Biosystems™ TaqMan™ OpenArray™ PGx Express Panel, QuantStudio™ 12K Flex

Applied Biosystems™ TaqMan™ OpenArray™ PGx Express Panel, QuantStudio™ 12K Flex

The TaqMan™ OpenArray™ PGx (Pharmacogenomics) Express Panel is an efficient, easy-to-use OpenArray™ plate for pharmacogenomics applications. The assays were developed to detect polymorphisms in genes encoding drug metabolism enzymes (DMEs) and associated transport proteins. This pharmacogenomics express panel contains 60 TaqMan™ DME and SNP genotyping assays. These assays provide coverage of essential, commonly studied markers within CYP2D6, CYP2C9, CYP2C19, and other important DME and clinical research genes.
Each TaqMan™ Drug Metabolism and SNP genotyping assay in the panel contains two allele-specific probes and a primer pair to detect the specific SNP target. Both the probes and primers uniquely align within the genome, enabling the TaqMan™ genotyping technology to provide superior specificity. It is this specificity that allows these assays to detect targets residing in highly homologous gene families that may include pseudogenes. TaqMan™ Drug Metabolism genotyping assays were developed using a high level of bioinformatics and wet-lab stringency. All assays have passed performance tests involving 180 unique DNA samples from four different populations.
The plate is pre-formatted and inventoried, cost-effective, convenient, and easy-to-use, without the need for expensive robotics. Results are reproducible and consistent across samples, studies, and labs—for the same data quality from plate-to-plate and lot-to-lot, even with different operators.

For use with equipment: QuantStudio™ 12k Flex

Contents

• Includes one OpenArray™ Plate containing a defined panel of pre-loaded, bench-validated TaqMan™ assays. Store at -5 to -30°C.