Applied Biosystems™ Pharma KingFisher™ Flex 96 Deep-Well Magnetic Particle Processor

Applied Biosystems™ Pharma KingFisher™ Flex 96 Deep-Well Magnetic Particle Processor

The Thermo Scientific™ Pharma KingFisher™ Flex 96 Deep-well Head Magnetic Particle Processor is intended for pharmaceutical analytics applications and is an excellent option for facilities that wish to automate their PrepSEQ™ Residual DNA or PrepSEQ™ 1-2-3 nucleic acid extraction kit protocols. The KingFisher Flex platform is a premier automated platform designed to meet your high-throughput needs. It seamlessly incorporates the rapid, reliable, and cost-effective magnetic bead-based extraction of nucleic acids that you expect from PrepSEQ technology with a 96-well automation system. Using magnetic particle separation technology, this system provides excellent reproducibility and quality.

Quantitative and consistent recovery of DNA from challenging matrices—including samples that have high protein concentration, low pH, or high salt—often presents a technical challenge. The PrepSEQ nucleic acid extraction kits are now adapted for higher-throughput workflows (up to 96 extractions, or 24 samples in triplicate) when used in combination with the KingFisher Flex 96 Deep-well Head Magnetic Particle Processor. The special formulation of magnetic particles provided in the PrepSEQ kits help ensure efficient and specific recovery of DNA from challenging samples.

Most automated liquid handling systems move reagents into and out of a single well to perform the different steps of nucleic acid isolation. In contrast, the KingFisher Flex 96 Deep-well Head Magnetic Particle Processor utilizes permanent rods to collect the magnetic beads from solution and releases the beads into a well containing reagents for the next step of isolation. The effectiveness of bead collection and transfer leads to superior washing, elution efficiency, and processing. The KingFisher Flex 96 Deep-well Head Magnetic Particle Processor can process up to 24 samples in triplicate, compared to 3 samples in triplicate using the manual method.

The KingFisher Flex 96 Deep-well Head Magnetic Particle Processor has been optimized to work with both the PrepSEQ Residual DNA Sample Preparation Kit and the PrepSEQ 1-2-3 Nucleic Acid Extraction Kit assays. The instrument comes pre-installed with PrepSEQ optimized protocols and does not require any further optimization after installation and validation.

Features

• Reliable recovery—quantitative and consistent nucleic acid recovery and cross-contamination control
• Efficient isolation—high-quality and high-throughput isolation of nucleic acids from Mycoplasma, Vesivirus, MMV, and residual DNA
• Streamlined design—superior performance and cost effectiveness per reaction
• Modular & versatile application—fully compatible with the PrepSEQ nucleic acid extraction kits