Gibco™ CTS™ TrueCut™ Cas9 Protein, 5.0 mg

Gibco™ CTS™ TrueCut™ Cas9 Protein, 5.0 mg

Gibco CTS TrueCut Cas9 Protein is our highest performing CRISPR-Cas9 protein, engineered to deliver maximum ribonucleoprotein (RNP)-editing efficiency. This protein is manufactured in compliance with standards for Ancillary Materials for Cell, Gene and Tissue-Based Products and is subjected to stringent quality specifications. It is provided in a high-concentration and large-scale format for process development and clinical research applications.

Features

• Consistent high editing efficiency—superior CRISPR-Cas9 editing efficiency in all tested cell lines including primary immune cells (>90% editing in primary T cells)
• Higher stringency manufacturing—manufactured to meet the standards for Ancillary Materials for Cell, Gene, and Tissue-Based Products including USP <1043>, Ph.Eur. 5.2.12, and ISO 20399 -1, -2, -3, following the principles of 21 CFR Part 820 in a FDA-registered manufacturing site
• Aseptic manufacturing—entire process completed using single-use technology
• Extensive safety testing—includes sterility, endotoxin, mycoplasma, residual nucleic acids, and proteins
• Sterile filling—finished product is vialed in a Class A/B (Class 100 and ISO 5 equivalents) cleanroom
• Traceability documentation—COA, COO, Drug Master Files, and Regulatory Support Files are available