Invitrogen 1 mg CD44 Monoclonal Antibody (IM7), Functional Grade, eBioscience™

Invitrogen 1 mg CD44 Monoclonal Antibody (IM7), Functional Grade, eBioscience™

The IM7 monoclonal antibody reacts with all isoforms of mouse CD44 (Pgp-1). CD44 is expressed by hematopoietic and non-hematopoietic cells. Bone marrow myeloid cells and memory T cells highly express this antigen and peripheral B and T cells can upregulate the expression of CD44. CD44 functions as an adhesion molecule through its binding to hyaluronate, an extracellular matrix component.

• Filtration: 0.2 µm post-manufacturing filtered.
• Purity: Greater than 90%, as determined by SDS-PAGE.
• Endotoxin Level: Less than 0.001 ng/µg antibody, as determined by LAL assay.
• Aggregation: Less than 10%, as determined by HPLC.
• Applications: Functional Assay (FN), Fluorescence Resonance Energy Transfer (FRET).
• Recommended Isotype Control: Rat IgG2b kappa Isotype Control (eB149/10H5), Functional Grade, eBioscience™.