Invitrogen 25 mg Ly-6G/Ly-6C Monoclonal Antibody (RB6-8C5), Functional Grade, eBioscience™

Invitrogen 25 mg Ly-6G/Ly-6C Monoclonal Antibody (RB6-8C5), Functional Grade, eBioscience™

The RB6-8C5 monoclonal antibody reacts with mouse Ly-6G, a 21-25 kDa protein also known as the myeloid differentiation antigen Gr-1. A GPI-linked protein, Gr-1 is expressed by the myeloid lineage in a developmentally regulated manner in the bone marrow. While monocytes only express Gr-1 transiently during their bone marrow development, the expression of Gr-1 on bone marrow granulocytes as well as on peripheral neutrophils is a good marker for these populations.

• Filtration: 0.2 µm post-manufacturing filtered.
• Purity: Greater than 90%, as determined by SDS-PAGE.
• Endotoxin Level: Less than 0.001 ng/µg antibody, as determined by LAL assay.
• Aggregation: Less than 10%, as determined by HPLC.
• Applications: Functional Assay (FN), Neutralization (Neu).
• Recommended Isotype Control: Rat IgG2b kappa Isotype Control (eB149/10H5), Functional Grade, eBioscience™