Invitrogen CD11b Monoclonal Antibody (M1/70), Biotin, 1 mg, eBioscience™

Invitrogen CD11b Monoclonal Antibody (M1/70), Biotin, 1 mg, eBioscience™

The M1/70 monoclonal antibody reacts with mouse CD11b, the 165-170 kDa integrin alphaM. CD11b non-covalently associates with CD18 to form alphaMbeta2 integrin (Mac-1) and binds to CD54 (ICAM-1), C3bi, and fibrinogen. Mac-1 is expressed by macrophages, NK cells, granulocytes, activated lymphocytes and mouse B-1 cells in the peritoneal cavity. M1/70 is also cross-reactive to human CD11b, and can be used for the detection of this antigen on human peripheral blood monocytes, granulocytes, and a subset of NK cells. Through interactions with its ligands, CD11b participates in adhesive cell interactions.

Applications: Functional Assay (FN).

Features

• Filtration: 0.2 µm post-manufacturing filtered.
• Recommended Isotype Control: Rat IgG2b kappa Isotype Control (eB149/10H5), Biotin, eBioscience™.