Invitrogen CD11c Monoclonal Antibody (N418), eFluor 450, 100 µg, eBioscience™

Invitrogen CD11c Monoclonal Antibody (N418), eFluor 450, 100 µg, eBioscience™

The N418 monoclonal antibody reacts with mouse CD11c, the integrin alphaX. CD11c non-covalently associates with beta2 integrin to form the CD11c/CD18 heterodimer. CD11c is expressed by dendritic cells, a subset of Intestinal Intraepithelial Lymphocytes (IEL) and some activated T cells. CD11c/CD18 binds to CD54, iC3b and fibrinogen and plays a role in leukocyte adhesive interactions. N418 binds to CD11c on splenic dendritic cells in the T-dependent areas of mouse spleen and precipitates a 150, 90 kDa heterodimer.

• eFluor® 450 is an alternative to Pacific Blue®. eFluor® 450 emits at 445 nm and is excited with the Violet laser (405 nm). Please make sure that your instrument is capable of detecting this fluorochome.
• Filtration: 0.2 µm post-manufacturing filtered.
• Recommended Isotype Control: Armenian Hamster IgG Isotype Control (eBio299Arm), eFluor 450, eBioscience™.