Invitrogen CD127 Monoclonal Antibody (eBioRDR5), Functional Grade, 100 µg, eBioscience™
On demandInvitrogen CD127 Monoclonal Antibody (eBioRDR5), Functional Grade, 100 µg, eBioscience™
The eBioRDR5 monoclonal antibody reacts with human CD127 (Interleukin-7 Receptor alpha). CD127 complexes with CD132, also known as the common gamma chain (gamma c), to form the multi-functional IL-7 receptor (IL-7R). CD127 is a type I glycoprotein with a molecular weight of 75-80 kDa and is expressed by immature B cells through the early pre-B stage, by thymocytes during several stages of their development, and on most mature T cells, with transient down-regulation upon activation. Binding of IL-7 results in signal transduction which occurs through several tyrosine kinase pathways including the Jak/STAT pathway. IL-7 is indispensible for the development of lymphocytes, and the control of homeostatic proliferation of T-cells in the periphery. In addition, IL-7R signaling is know to be involved in the regulation of T cell receptor (TCR) locus rearrangement in gamma delta T cells.
Applications: Functional Assay (FN).
Features
- Filtration: 0.2 µm post-manufacturing filtered.
- Purity: Greater than 90%, as determined by SDS-PAGE.
- Endotoxin Level: Less than 0.001 ng/µg antibody, as determined by LAL assay.
- Aggregation: Less than 10%, as determined by HPLC.
- Recommended Isotype Control: Mouse IgG1 kappa Isotype Control (P3.6.2.8.1), Functional Grade, eBioscience™.
There are no specifications
There are no report
You May Also Like
Invitrogen CD4 Monoclonal Antibody (RM4-5), FITC, 1 mg, eBioscience™
$ On demand
On demand
Invitrogen 25 µg Ly-6G/Ly-6C Monoclonal Antibody (RB6-8C5), Brilliant Ultra Violet 805, eBioscience™
$ On demand
On demand
Invitrogen 25 µg MHC Class II (I-A/I-E) Monoclonal Antibody (M5/114.15.2), eFluor 450, eBioscience™
$ On demand
On demand
Invitrogen CD45 Monoclonal Antibody (30-F11), NovaFluor Blue 585, 25 µg, eBioscience™
$ On demand
On demand
Invitrogen IL-22 Monoclonal Antibody (IL22JOP), Functional Grade, 50 mg, eBioscience™
$ On demand
On demand
Invitrogen Armenian Hamster IgG Isotype Control (eBio299Arm), eFluor 660, 100 µg, eBioscience™
$ On demand
On demand
Invitrogen 25 µg Rat IgG2b kappa Isotype Control (eB149/10H5), eFluor 506, eBioscience™
$ On demand