Invitrogen CD127 Monoclonal Antibody (eBioRDR5), PE-Cyanine7, 100 Tests, eBioscience™
On demandInvitrogen CD127 Monoclonal Antibody (eBioRDR5), PE-Cyanine7, 100 Tests, eBioscience™
The eBioRDR5 monoclonal antibody reacts with human CD127 (Interleukin-7 Receptor alpha). CD127 complexes with CD132, also known as the common gamma chain (gamma c), to form the multi-functional IL-7 receptor (IL-7R). CD127 is a type I glycoprotein with a molecular weight of 75-80 kDa and is expressed by immature B cells through the early pre-B stage, by thymocytes during several stages of their development, and on most mature T cells, with transient down-regulation upon activation. Binding of IL-7 results in signal transduction which occurs through several tyrosine kinase pathways including the Jak/STAT pathway. IL-7 is indispensible for the development of lymphocytes, and the control of homeostatic proliferation of T-cells in the periphery. In addition, IL-7R signaling is know to be involved in the regulation of T cell receptor (TCR) locus rearrangement in gamma delta T cells.
Features
- Light sensitivity: This tandem dye is sensitive photo-induced oxidation. Please protect this vial and stained samples from light.
- Fixation: Samples can be stored in IC Fixation Buffer (100 µL cell sample + 100 µL IC Fixation Buffer) or 1-step Fix/Lyse Solution for up to 3 days in the dark at 4°C with minimal impact on brightness and FRET efficiency/compensation. Some generalizations regarding fluorophore performance after fixation can be made, but clone specific performance should be determined empirically.
- Excitation: 488-561 nm; Emission: 775 nm; Laser: Blue Laser, Green Laser, Yellow-Green Laser.
- Filtration: 0.2 µm post-manufacturing filtered.
- Recommended Isotype Control: Mouse IgG1 kappa Isotype Control (P3.6.2.8.1), PE-Cyanine7, eBioscience™.
There are no specifications
There are no report
You May Also Like
![](https://laboshop.ae/public/storage/files/4a811ae8-82da-4a61-82f1-006cca36592d.png)
Invitrogen CD62L (L-Selectin) Monoclonal Antibody (MEL-14), Functional Grade, 50 mg, eBioscience™
$ On demand
On demand
![](https://laboshop.ae/public/storage/files/5550a4e8-8bb3-40ae-ad38-adfc120a71b0.png)
Invitrogen CD80 (B7-1) Monoclonal Antibody (2D10.4), FITC, 100 Tests, eBioscience™
$ 258
On demand
![](https://laboshop.ae/public/storage/files/f5455a50-6fab-42df-b75c-e4029933286d.png)
Invitrogen CD16 Monoclonal Antibody (eBioCB16 (CB16)), Super Bright™ 436, 100 Tests, eBioscience™
$ On demand
On demand
![](https://laboshop.ae/public/storage/files/62a30841-9012-4d93-bb79-6a9e64ea97b8.png)
Invitrogen Mouse IgG2b kappa Isotype Control (eBMG2b), eFluor 615, 25 µg, eBioscience™
$ On demand
On demand
![](https://laboshop.ae/public/storage/files/8a701cd9-f8d8-4ad2-a49a-89a9c37fabb7.png)
Invitrogen 100 µg Rat IgG2a kappa Isotype Control (eBR2a), Functional Grade, eBioscience™
$ On demand
On demand
![](https://laboshop.ae/public/storage/files/4c94302a-34c3-4e7f-92c5-5f182fac194e.png)
Invitrogen T-bet Monoclonal Antibody (eBio4B10 (4B10)), PE, 100 µg, eBioscience™
$ On demand
On demand
![](https://laboshop.ae/public/storage/files/4283eed2-733b-48be-8834-82352bf811a6.png)
Invitrogen CD54 (ICAM-1) Monoclonal Antibody (HA58), NovaFluor™ Red 685, 100 Tests, eBioscience™
$ On demand