Invitrogen CD127 Monoclonal Antibody (eBioRDR5), Super Bright 780, 100 Tests, eBioscience™
On demandInvitrogen CD127 Monoclonal Antibody (eBioRDR5), Super Bright 780, 100 Tests, eBioscience™
The eBioRDR5 monoclonal antibody reacts with human CD127 (Interleukin-7 Receptor alpha). CD127 complexes with CD132, also known as the common gamma chain (gamma c), to form the multi-functional IL-7 receptor (IL-7R). CD127 is a type I glycoprotein with a molecular weight of 75-80 kDa and is expressed by immature B cells through the early pre-B stage, by thymocytes during several stages of their development, and on most mature T cells, with transient down-regulation upon activation. Binding of IL-7 results in signal transduction which occurs through several tyrosine kinase pathways including the Jak/STAT pathway. IL-7 is indispensible for the development of lymphocytes, and the control of homeostatic proliferation of T-cells in the periphery. In addition, IL-7R signaling is know to be involved in the regulation of T cell receptor (TCR) locus rearrangement in gamma delta T cells.
Features
- Super Bright 780 is a tandem dye that can be excited with the violet laser line (405 nm) and emits at 780 nm. We recommend using a 780/60 bandpass filter. Please make sure that your instrument is capable of detecting this fluorochrome.
- When using two or more Super Bright dye-conjugated antibodies in a staining panel, it is recommended to use Super Bright Complete Staining Buffer to minimize any non-specific polymer interactions. Please refer to the datasheet for Super Bright Staining Buffer for more information.
- Light sensitivity: This tandem dye is sensitive to photo-induced oxidation. Please protect this vial and stained samples from light.
- Fixation: Samples can be stored in IC Fixation Buffer (100 µL of cell sample + 100 µL of IC Fixation Buffer) or 1-step Fix/Lyse Solution for up to 3 days in the dark at 4°C with minimal impact on brightness and FRET efficiency/compensation. Some generalizations regarding fluorophore performance after fixation can be made, but clone specific performance should be determined empirically.
- Excitation: 405 nm; Emission: 780 nm; Laser: Violet Laser.
- Recommended Isotype Control: Mouse IgG1 kappa Isotype Control (P3.6.2.8.1), Super Bright 780, eBioscience™.
There are no specifications
There are no report
You May Also Like
![](https://laboshop.ae/public/storage/files/87d7b5dc-8547-46a2-98b7-f261b8e2a676.png)
Invitrogen CD80 (B7-1) Monoclonal Antibody (2D10.4), PE-Cyanine5, 100 Tests, eBioscience™
$ 400
On demand
![](https://laboshop.ae/public/storage/files/5b1e4ba8-b78f-4fc9-afec-cdd09f2c196a.png)
Invitrogen CD83 Monoclonal Antibody (HB15e), FITC, 100 Tests, eBioscience™
$ 336
On demand
![](https://laboshop.ae/public/storage/files/dc814a0d-9de9-4d98-8fc6-5b50af3616cb.png)
Invitrogen CD4 Monoclonal Antibody (SK3 (SK-3)), NovaFluor Yellow 570, 25 Tests, eBioscience™
$ On demand
On demand
![](https://laboshop.ae/public/storage/files/a84baad3-334f-4cf2-96c2-6426c9d18caf.png)
Invitrogen CD90.2 (Thy-1.2) Monoclonal Antibody (53-2.1), APC, 200 µg, eBioscience™
$ 503
On demand
![](https://laboshop.ae/public/storage/files/087272ee-8e05-4b76-bb08-863b972dda00.png)
Invitrogen CD45RO Monoclonal Antibody (UCHL1), Unconjugated, 100 µg, eBioscience™
$ 152
On demand
![](https://laboshop.ae/public/storage/files/820f89f8-f8c2-4428-9f1d-2d2dc9bad822.png)
Invitrogen 500 µg Ly-6G/Ly-6C Monoclonal Antibody (RB6-8C5), FITC, eBioscience™
$ On demand
On demand
![](https://laboshop.ae/public/storage/files/284e4b82-3070-413c-999e-734120939041.png)
Invitrogen IL-1 beta (Pro-form) Monoclonal Antibody (NJTEN3), APC-eFluor 780, 100 µg, eBioscience™
$ On demand
On demand
![](https://laboshop.ae/public/storage/files/e42ad669-c706-4f74-9dca-8fb987fb685f.png)
Invitrogen Granzyme B Monoclonal Antibody (NGZB), eFluor™ 660, 100 µg, eBioscience™
$ On demand