Invitrogen CD16 Monoclonal Antibody (eBioCB16 (CB16)), PE, 25 Tests, eBioscience™
On demandInvitrogen CD16 Monoclonal Antibody (eBioCB16 (CB16)), PE, 25 Tests, eBioscience™
The eBioCB16 monoclonal antibody recognizes CD16 (Fc gammaRIII), the low-affinity receptor for IgG with an apparent molecular weight of 50-80 kDa. CD16 is represented by two similar genes, CD16A (Fc gammaRIIIA), which exists as a hetero-oligomeric polypeptide-anchored form in macrophages and NK cells and CD16B (Fc gammaRIIIB), which exist as a monomeric GPI-anchored form in neutrophils. Furthermore, there are two known polymorphisms of CD16B, NA-1 and NA-2. Individuals homozygous for NA-2 show a lower phagocytic capacity compared with NA-1. CD16 binds IgG in the form of immune complexes and shows preferential binding of IgG1 and IgG3 isotypes and minimal binding of IgG2 and IgG4. Upon IgG binding, both CD16 isoforms initiate signal transduction cascades that lead to a variety of responses including antibody-dependent cell-mediated cytotoxicity (ADCC), phagocytosis, degranulation and proliferation.
Filtration: 0.2 µm post-manufacturing filtered.
MoreThere are no specifications
There are no report
You May Also Like
Invitrogen CD41a Monoclonal Antibody (eBioMWReg30 (MWReg30)), PerCP-eFluor 710, 25 µg, eBioscience™
$ On demand
On demand
Invitrogen Mouse IgG2b kappa Isotype Control (eBMG2b), eFluor 660, 100 µg, eBioscience™
$ On demand
On demand
Invitrogen CD45RO Monoclonal Antibody (UCHL1), Super Bright™ 702, 100 Tests, eBioscience™
$ 435
On demand
Invitrogen CD59 (Protectin) Monoclonal Antibody (OV9A2), Super Bright™ 600, 100 Tests, eBioscience™
$ 452
On demand
Invitrogen CD71 (Transferrin Receptor) Monoclonal Antibody (OKT9 (OKT-9)), Biotin, 100 µg, eBioscience™
$ On demand
On demand
Invitrogen Rat IgG1 kappa Isotype Control (eBRG1), eFluor 660, 25 µg, eBioscience™
$ On demand