Invitrogen CD197 (CCR7) Monoclonal Antibody (3D12), PE, 25 Tests, eBioscience™
On demandInvitrogen CD197 (CCR7) Monoclonal Antibody (3D12), PE, 25 Tests, eBioscience™
The 3D12 monoclonal antibody reacts with human CCR7, also known as EBI-1 and CD197. CCR7 is a member of the G-protein-coupled chemokine receptor family with seven membrane-spanning domains and functions as a receptor for 6Ckine/SLC (secondary lymphoid-tissue chemokine), CCL19 and CCL21. CCR7 has been shown to be internalized via clathrin-coated pits and the majority recycled back to the plasma membrane. CCR7 is expressed on T cells and can be used to distinguish populations of naive from central and effector memory T cells. CCR7 has been shown to play a role in migration of memory T cells to inflamed tissue. Expression of CCR7 is also found on DC's. During DC maturation CCR7 expression increases and is thought to be involved in a variety of functions: chemotaxis to the lymph node, cellular architecture, rate of endocytosis, survival and maturation. Expression of CCR7 on the cell surface can be down regulated upon ligand binding.
Features
- Excitation: 488-561 nm; Emission: 578 nm; Laser: Blue Laser, Green Laser, Yellow-Green Laser.
- Filtration: 0.2 µm post-manufacturing filtered.
There are no specifications
There are no report
You May Also Like
Invitrogen GAPDH Loading Control Monoclonal Antibody (GA1R), Alexa Fluor 488
$ On demand
On demand
Invitrogen Gata-3 Monoclonal Antibody (TWAJ), PE, 100 Tests, eBioscience™
$ On demand
On demand
Invitrogen 25 µg Rat IgG2b kappa Isotype Control (eB149/10H5), Super Bright 702, eBioscience™
$ On demand
On demand
Invitrogen CD62L (L-Selectin) Monoclonal Antibody (MEL-14), APC, 50 µg, eBioscience™
$ On demand
On demand
Invitrogen 100 µg CD133 (Prominin-1) Monoclonal Antibody (13A4), Unconjugated, eBioscience™
$ On demand
On demand
Invitrogen Mouse IgG2b kappa Isotype Control (eBMG2b), PE-Cyanine5, 100 Tests, eBioscience™
$ On demand