Invitrogen CD4 Monoclonal Antibody (RM4-5), eFluor™ 450, 25 µg, eBioscience™

Invitrogen CD4 Monoclonal Antibody (RM4-5), eFluor™ 450, 25 µg, eBioscience™

The RM4-5 monoclonal antibody reacts with the mouse CD4 molecule, a 55 kDa cell surface receptor expressed by a majority of thymocytes, subpopulation of mature T cells and dendritic cells. CD4 binds to MHC class II on the surface of antigen presenting cells and plays an important role both in T cell development and in optimal functioning of mature T cells. In T cells, CD4 associates with protein tyrosine kinase p56lck through its cytoplasmic tail. Binding of RM4-5 is blocked by GK1.5.

Features

• Excitation: 405 nm; Emission: 445 nm; Laser: Violet Laser.
• Filtration: 0.2 µm post-manufacturing filtered.
• Recommended Isotype Control: Rat IgG2a kappa Isotype Control (eBR2a), eFluor™ 450, eBioscience™.