Invitrogen CD49d (Integrin alpha 4) Monoclonal Antibody (9F10), Functional Grade, 50 µg, eBioscience™

Invitrogen CD49d (Integrin alpha 4) Monoclonal Antibody (9F10), Functional Grade, 50 µg, eBioscience™

The 9F10 monoclonal antibody reacts with human CD49d, the 150 kDa integrin alpha4 subunit. The complex of CD49d non-covalently associated with integrin beta1 (CD29), also known as VLA-4, is a receptor for fibronectin and VCAM-1 (CD106). This complex is expressed by thymocytes, peripheral lymphocytes, monocytes and eosinophils. CD49d also associates with integrin beta7 and binds to the Mucosal Addressin Cell-Adhesion Molecule-1 (MadCAM-1).

Applications: Functional Assay (FN).

Features  

• Storage and handling: Use in a sterile environment.
• Filtration: 0.2 µm post-manufacturing filtered.
• Purity: Greater than 90%, as determined by SDS-PAGE.
• Endotoxin Level: Less than 0.001 ng/µg antibody, as determined by LAL assay.
• Aggregation: Less than 10%, as determined by HPLC.