Invitrogen CD62L (L-Selectin) Monoclonal Antibody (MEL-14), eFluor 450, 25 µg, eBioscience™

Invitrogen CD62L (L-Selectin) Monoclonal Antibody (MEL-14), eFluor 450, 25 µg, eBioscience™

The MEL-14 monoclonal antibody reacts with mouse CD62L, a 76 kDa member of the selectin family. CD62L is expressed by neutrophils, monocytes, and subsets of T, B, and NK cells and binds a number of glycosylated, fucosylated, sulfated sialylated glycoproteins including CD34, glycam-1 and MAdCam-1. These interactions mediate rolling of lymphocytes on activated endothelium at the sites of inflammation and homing of cells to the high endothelial venules (HEV) of peripheral lymphoid tissues.

Features

• eFluor® 450 is an alternative to Pacific Blue®. eFluor® 450 emits at 445 nm and is excited with the Violet laser (405 nm). Please make sure that your instrument is capable of detecting this fluorochome.
• Excitation: 405 nm; Emission: 445 nm; Laser: Violet Laser.
• Filtration: 0.2 µm post-manufacturing filtered.
• Recommended Isotype Control: Rat IgG2a kappa Isotype Control (eBR2a), eFluor 450, eBioscience™.