Invitrogen CD62L (L-Selectin) Monoclonal Antibody (MEL-14), Super Bright 436, 100 µg, eBioscience™

Invitrogen CD62L (L-Selectin) Monoclonal Antibody (MEL-14), Super Bright 436, 100 µg, eBioscience™

The MEL-14 monoclonal antibody reacts with mouse CD62L, a 76 kDa member of the selectin family. CD62L is expressed by neutrophils, monocytes, and subsets of T, B, and NK cells and binds a number of glycosylated, fucosylated, sulfated sialylated glycoproteins including CD34, glycam-1 and MAdCam-1. These interactions mediate rolling of lymphocytes on activated endothelium at the sites of inflammation and homing of cells to the high endothelial venules (HEV) of peripheral lymphoid tissues.

Features

• Super Bright 436 can be excited with the violet laser line (405 nm) and emits at 436 nm. We recommend using a 450/50 bandpass filter, or equivalent. Please make sure that your instrument is capable of detecting this fluorochrome.
• When using two or more Super Bright dye-conjugated antibodies in a staining panel, it is recommended to use Super Bright Complete Staining Buffer to minimize any non-specific polymer interactions. Please refer to the datasheet for Super Bright Staining Buffer for more information.
• Excitation: 405 nm; Emission: 436 nm; Laser: Violet Laser.
• Recommended Isotype Control: Rat IgG2a kappa Isotype Control (eBR2a), Super Bright 436, eBioscience™.