Invitrogen IL-13 Monoclonal Antibody (eBio13A), eFluor 450, 25 µg, eBioscience™

Invitrogen IL-13 Monoclonal Antibody (eBio13A), eFluor 450, 25 µg, eBioscience™

The eBio13A antibody reacts with mouse IL-13. IL-13 is a cytokine produced mainly by Th2 cells, but also by antigen-primed CD8 T cells. IL-13 has a strong involvement in allergic inflammation and parasitic clearing and in cancer models has been shown to have either inhibitory or stimulatory activity depending on the tumor. In humans, IL-13 is found to play a role in isotype switching in B cells. IL-13 is implicating in down modulating macrophage activity, through the reduction of pro-inflammatory cytokines (IL-1, IL-6, IL-8, IL-10, IL-12).

• eFluor® 450 is an alternative to Pacific Blue®. eFluor® 450 emits at 445 nm and is excited with the Violet laser (405 nm). Please make sure that your instrument is capable of detecting this fluorochome.
• Excitation: 405 nm; Emission: 445 nm; Laser: Violet Laser.
• Filtration: 0.2 µm post-manufacturing filtered.
• Applications: Neutralization (Neu). 
• Recommended Isotype Control: Rat IgG1 kappa Isotype Control (eBRG1), eFluor 450, eBioscience™.