Invitrogen™ Valinomycin
On demand
Order number :
V1644
Invitrogen™ Valinomycin
Valinomycin is a natural, lipid-soluble molecule (Mr = ∼1,110) that
binds potassium ions (K+) and facilitates their transfer across lipid
bilayers (i.e., it is an ionophore). It is a macrocyclic molecule formed
from 12 alternating amino acids and esters, synthesized by specific Streptomyces.
Valinomycin exhibits a 10,000-fold selectivity for K+ over Na+.
Valinomycin is a potent antibiotic. It is commonly used as an agent to
induce apoptosis and can also be used to calibrate potentiometric
responses in membrane experiments involving potential-sensitive dyes
such as di-4-ANEPPS.
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