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JAK2, (FISH)

On demand
Order number : HE-F04
(Ex-work price)
$ On demand

9p24 translocation or amplification 


Main indication:

MPD with Negative JAK2 617V mutation.


Test usage:

The JAK2 gene is a protein tyrosine kinase involved in cytokine signaling. Chromosomal translocations involving JAK2 can lead to the formation of chimeric oncoproteins in hematologic malignancies. Rearrangements involving 9p24.1 are typically aggressive and rare abnormalities seen in various hematologic diseases. JAK2 inhibitors are one of the only therapy options besides a stem cell transplant for JAK2 rearrangements.

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NO related applications

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