Thermo Scientific™ CaptureSelect™ Biotin Anti-IgG-CH1 Conjugate, 100 µg

Thermo Scientific™ CaptureSelect™ Biotin Anti-IgG-CH1 Conjugate, 100 µg

CaptureSelect™ Biotin Anti-IgG-CH1 Conjugate consists of a 14 kDa llama antibody fragment (affinity ligand) that specifically binds to the CH1 domain of all four human IgG subclasses. The affinity ligand is chemically conjugated to biotin via an appropriate spacer that retains the binding reactivity of the ligand when used in combination with streptavidin-based conjugates or streptavidin pre-coated surfaces.

Features

• Detect, quantitate, and characterize all human IgG antibodies (subclasses 1 to 4) and Fab fragments thereof, independent of light chain type, and total IgG in human plasma and/or serum samples
• Avoid cross-binding with other isotypes, such as IgA, IgM, IgD, and IgE, free light chains, or IgG from mouse sources or bovine sources such as FCS
• Screen antibody-antigen interactions—biotin anti-IgG-CH1 forms a stable [low k(diss)] complex with human IgG antibodies through bivalent binding