Thermo Scientific™ CaptureSelect™ Factor X Affinity Matrix, 1 L

Thermo Scientific™ CaptureSelect™ Factor X Affinity Matrix, 1 L

CaptureSelect Factor X Affinity Matrix was specifically designed for the purification of human Factor X from plasma and recombinant sources.

Coagulation Factor X is a vitamin K-dependent, liver-produced serine protease that serves as the first enzyme in the coagulation cascade to form fibrin. It is a two-chain glycoprotein with a molecular weight of approximately 59 kDa. Factor X normally circulates in the plasma as an inactive molecule with activation of Factor X involved in both the intrinsic and extrinsic coagulation pathways.

Features

• Highly selective for human Factor X with no affinity for other human plasma proteins
• Binds both Factor X and Factor Xa in the presence of calcium
• Enables efficient purification of Factor X with high yields and retained activity
• Mild elution at neutral pH using EDTA
• Offers excellent scalability
• Non-animal-derived