Thermo Scientific™ CaptureSelect™ LC-lambda (mouse) Affinity Matrix, 10 mL

Thermo Scientific™ CaptureSelect™ LC-lambda (mouse) Affinity Matrix, 10 mL

The CaptureSelect™ LC-lambda (mouse) Affinity Matrix contains a 13 kDa llama antibody fragment recognizing the lambda light chain of mouse Ig’s. The ligand is directed towards a unique domain on the constant part of the lambda light chain of immunoglobulins, which enables purification of mouse immunoglobulins and fab fragments without cross reactivity towards bovine immunoglobulins. This makes the CaptureSelect™ LC-lambda (mouse) Affinity Matrix a unique resin in terms of specificity. The ligand is coupled on a 70 µm aldehyde-activated agarose bead. This matrix can be used for the purification and isolation of lambda light chain-containing mouse immunoglobulins and fab fragments from complex sources like cell culture supernatants, plasma, and serum in a single step. Due to its non-reactivity to bovine Ig, FCS can be applied in growth media without disturbing purification.