Thermo Scientific™ HyPerforma™ Enhanced Single-Use Fermentor, jacketed, AC motor, 4-position vent filter bracket, 300 L

Thermo Scientific™ HyPerforma™ Enhanced Single-Use Fermentor, jacketed, AC motor, 4-position vent filter bracket

This Thermo Scientific HyPerforma Enhanced Single-Use Fermentor (eS.U.F.) is designed to provide users with enhanced functionality, ease of use, and efficiency for microbial fermentation. Enhanced jacketing provides 35% increased surface area, improving temperature control capabilities by at least 21%. The HyPerforma eS.U.F. system consists of a fermentor tank and HyPerforma Enhanced S.U.F. BioProcess Container (BPC). The system has a 5:1 turndown ratio, so it can run at a low 60-L working volume. The HyPerforma S.U.F. maintains traditional stirred-tank fermentation design principles, including specific height-to-diameter ratios (3:1), a top-driven impeller location that delivers optimum cell viability, and performance and scalability from process development through production.

Features

• Enhanced jacketing for a 35% increase in jacketed surface area and improved heat transfer
• Fully functional fermentor vessel including single-use sterile contact surfaces for mixing, venting, sparging, and temperature sensing and additional ports to allow choice of aseptic connections for filling, emptying, and sampling
• Unique proprietary mixing system that enables conventional overhead mixing while maintaining sterility and integrity of the BPC
• Minimized vessel footprint and reduced hold-up volumes
• Simplified bag loading with front access door
• A tank with baffles for enhanced mixing
• Cable/tubing management system that offers greater organization for electrical cables and tubing
• Enhanced BPC that utilizes three re-designed turbine impellers and sparger configuration with proprietary exhaust management system
• State-of-the-art foam sensor that helps prevent exhaust filter failure

Applications of the Thermo Scientific HyPerforma S.U.F. include:

• Proven for various microbial cultures of Pichia, Bacillus and others.
• Batch and fed-batch cultures.