Thermo Scientific™ Pierce™ p-Bromophenacylate Reagent

Thermo Scientific™ Pierce™ p-Bromophenacylate Reagent

p-Bromophenacyl-8™ Reagent is an excellent derivatization reagent that reacts with carboxylic acids. This reagent is used for preparing phenacyl esters, which are used to separate many saturated and unsaturated fatty acids1-2 for UV detection in HPLC applications with low nanomole sensitivity. p-Bromophenacyl-8™ Reagent is also useful for studying acid composition of bacterial cell walls.

Features

• Premixing of phenacylbromide and crown ether is not necessary
• Derivatization is both rapid and quantitative, with yields of >95% in 15 to 20 minutes at 80°C
• Excess reactants do not interfere
• Large excess of alkylating reagent is not necessary
• Small amounts of water or alcohol do not interfere
• If isolation is desired, products are usually crystalline