Thermo Scientific™ Pierce™ Traut's Reagent (2-iminothiolane)

Thermo Scientific™ Pierce™ Traut's Reagent (2-iminothiolane)

Thermo Scientific Pierce Traut's Reagent (2-iminothiolane) is a small thiolation compound that reacts with primary amines (e.g., lysine side chains) to add a small spacer arm (8.1 angstroms) terminated by a free sulfhydryl group.

Features

• Simple—one-step conversion of amines to sulfhydryls
• Specific—selective and spontaneous modification of primary amines at pH 7-10
• Preserves positive charge to maintain protein solubility