13q [RB1/13q34 (RB1/LAMP1)] Probe Detection Kit (IVD)
On demand
Brand origin :
China
Expiry time :
On demand
Delivery time :
1 Week/s
Delivery cost :
On demand
Unit size :
10 Tests
Order number :
FP-305
13q [RB1/13q34 (RB1/LAMP1)] Probe Detection Kit (IVD)
The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma. [provided by RefSeq, Jul 2008].
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