Applied Biosystems™ GeneChip™ Mouse Gene 1.1 ST, 96 Array Plate

Applied Biosystems™ GeneChip™ Mouse Gene 1.1 ST, 96 Array Plate

The Mouse Gene 1.1 ST 24-Array Plate and Trays enables high-throughput expression profiling of 24 samples at a time using the same content as the industry-standard GeneChip™ Mouse Gene 1.0 ST Array

esearch over the past 20 years has predominantly focused on protein-coding messenger RNA transcripts and their role in cellular processes, such as disease and development. Recently researchers have identified more that 2,000 transcripts (>200 bases) in the mouse genome with little or no protein coding potential. Only a small fraction of these non-coding RNAs has functional annotations to date. However, there is ample evidence that differential expression of lincRNAs plays an important role in the genesis and progression of disease and that aberrant expression of these molecules have also been linked to cancer.

Features

• Comprehensive coverage provides the best opportunity to discover interesting biology

   - >28,000 coding transcripts

   - >7,000 non-coding (include ˜2,000) long intergenic non-coding transcripts

• Measure alternative splicing events/transcript variants with probes designed to maximize exon coverage
• Reproducible: Intra-lot correlation coefficient = 0.99