BCL6, (Tissue - FISH)
On demand
Order number :
ST-F15
Detection of 3q27 translocations
Main indication:
DLBCL.
Test usage:
The B-cell lymphoma 6 (BCL6) gene is localized to 3q27. Rearrangements of 3q27 may be seen in case diffuse large B-cell lymphoma (30-40%) and follicular lymphoma (5-15%). Structural rearrangements include translocations and microdeletions, with about one-half of the translocations involving the immunoglobulin genes at 14q32, 2p12 and 22q13. The remaining translocations involve 3q27 with a wide variety of other chromosome partners.
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