Invitrogen CD28 Monoclonal Antibody (37.51), Functional Grade, 25 mg, eBioscience™

Invitrogen CD28 Monoclonal Antibody (37.51), Functional Grade, 25 mg, eBioscience™

The 37.51 monoclonal antibody reacts with the mouse CD28 molecule, a 45 kDa homodimer expressed by thymocytes, mature T cells and NK cells. CD28 is a ligand for CD80 (B7-1) and CD86 (B7-2) and is a potent costimulator of T cells. Signaling through CD28 augments IL-2 and IL-2 receptor expression as well as cytotoxicity of CD3-activated T cells.

Applications: Functional Assay (FN), T-Cell Activation (TCA) and In vitro Assay (IV).

Features

• Storage and handling: Use in a sterile environment.
• Filtration: 0.2 µm post-manufacturing filtered.
• Purity: Greater than 90%, as determined by SDS-PAGE.
• Endotoxin Level: Less than 0.001 ng/µg antibody, as determined by LAL assay.
• Aggregation: Less than 10%, as determined by HPLC.