Invitrogen CD4 Monoclonal Antibody (GK1.5), FITC, 100 µg, eBioscience™

Invitrogen CD4 Monoclonal Antibody (GK1.5), FITC, 100 µg, eBioscience™

The GK1.5 monoclonal antibody reacts with the mouse CD4 molecule, a 55 kDa cell surface receptor expressed by a majority of thymocytes, subpopulation of mature T cells and dendritic cells. CD4 binds to MHC class II on the surface of antigen presenting cells and plays an important role both in T cell development and in optimal functioning of mature T cells. In T cells, CD4 associates with protein tyrosine kinase p56lck through its cytoplasmic tail. Binding of GK1.5 is blocked by RM4-5.

Filtration: 0.2 µm post-manufacturing filtered.

Applications: Functionl Assay (FN).