Invitrogen CD41a Monoclonal Antibody (eBioMWReg30 (MWReg30)), PE, 100 µg, eBioscience™
On demandInvitrogen CD41a Monoclonal Antibody (eBioMWReg30 (MWReg30)), PE, 100 µg, eBioscience™
The eBioMWReg30 monoclonal antibody reacts with mouse CD41 (fibrinogen receptor, gpIIb, integrin alpha IIb). While initially thought to be expressed exclusively on the surface of platelets and megakaryocytes, it has been demonstrated that CD41 is also expressed on hematopoietic progenitors in the embryo, fetus and adult. CD41 associates with CD61 (gpIIIa, integrin beta III) to form a receptor which plays a major role in platelet function, including binding of several adhesion molecules such as fibrinogen, fibronectin and vitronectin.
Recently, the SLAM-family markers, CD48 and CD150 have been used to reliably identify hematopoietic stem cells (HSC). Specifically, it was found that CD150+CD48- bone marrow cells were highly efficient in their ability to confer long-term multi-lineage reconstitution in irradiated mice. Furthermore, the efficiency of reconstitution was enhanced when HSCs were further enriched through the exclusion of CD41+ cells. Thus, the use of CD150+CD48-CD41- as an expression profile efficiently identifies hematopoietic stem cells.
- Excitation: 488-561 nm; Emission: 578 nm; Laser: Blue Laser, Green Laser, Yellow-Green Laser.
- Filtration: 0.2 µm post-manufacturing filtered.
- Recommended Isotype Control: Rat IgG1 kappa Isotype Control (eBRG1), PE, eBioscience™.
There are no specifications
There are no report
You May Also Like
![](https://laboshop.ae/public/storage/files/e3b29d21-67b3-492d-8a87-c51c183eedbd.png)
Invitrogen 25 µg Rat IgG2b kappa Isotype Control (eB149/10H5), eFluor 506, eBioscience™
$ On demand
On demand
![](https://laboshop.ae/public/storage/files/dea556ff-5e0f-46d9-893d-959bdb889f8b.png)
Invitrogen CD45RO Monoclonal Antibody (UCHL1), PE-Cyanine5, 100 Tests, eBioscience™
$ 349
On demand
![](https://laboshop.ae/public/storage/files/fff27e18-3593-45fc-938b-308bd04991bf.png)
Invitrogen 100 µg Rat IgG2a kappa Isotype Control (eBR2a), PE, eBioscience™
$ On demand
On demand
![](https://laboshop.ae/public/storage/files/aa863a27-b7fa-4eb0-8c56-6c0f37047f2c.png)
Invitrogen Granzyme B Monoclonal Antibody (NGZB), PE-Cyanine7, 100 µg, eBioscience™
$ On demand
On demand
![](https://laboshop.ae/public/storage/files/99d98ec0-dd78-4a9e-9938-fb4f2ec1ea61.png)
Invitrogen CD3e Monoclonal Antibody (145-2C11), Functional Grade, 25 mg, eBioscience™
$ On demand
On demand
![](https://laboshop.ae/public/storage/files/639455ea-1928-4396-9128-0a69b0ae9760.png)
Invitrogen CD49f (Integrin alpha 6) Monoclonal Antibody (eBioGoH3 (GoH3)), APC-eFluor™ 780, 25 µg, eBioscience™
$ 227
On demand
![](https://laboshop.ae/public/storage/files/aa7b3225-7ca3-4147-bf53-96d932a42c3e.png)
Invitrogen CD49f (Integrin alpha 6) Monoclonal Antibody (eBioGoH3 (GoH3)), FITC, 25 µg, eBioscience™
$ 126