Invitrogen™ Concanavalin A, succinylated, Alexa Fluor™ 488 Conjugate

Invitrogen™ Concanavalin A, succinylated, Alexa Fluor™ 488 Conjugate

This green-fluorescent Alexa Fluor 488 conjugate of succinylated concanavalin A (Con A) selectively binds to α-mannopyranosyl and α-glucopyranosyl residues. In acidic solutions (pH 4.5—5.6), Con A exists as a dimer with molecular weight of approximately 52,000 daltons; above pH 7, it is primarily a tetramer with a molecular weight of 104,000 daltons. Succinylation of Con A prevents tetramer formation, thus greatly reducing the lectin's agglutination activity but not its reactivity with glucose and mannose residues.