Invitrogen Gata-3 Monoclonal Antibody (TWAJ), PE, 100 Tests, eBioscience™
On demandInvitrogen Gata-3 Monoclonal Antibody (TWAJ), PE, 100 Tests, eBioscience™
The monoclonal antibody TWAJ recognizes mouse and human Gata-3, a member of the Gata family of transcription factors. Gata-3 is a T cell-specific transcription factor important for thymic development and Th2 differentiation. Expression during embryonic development is found in the central nervous system, skin, mammary glands and kidney. During development, the expression of Gata-3 is essential as homozygous knock-out of Gata-3 is embryonic lethal. The Gata-3 is also essential for T cell commitment and survival. In the thymus, expression is found mainly on the CD4 single positive cells. During Th2 differentiation, Gata-3 binds to the IL-4 promoter as well as represses the expression of T-bet, thus inhibiting Th1 differentiation.
Alternative splice variants have been reported especially in the MCF7 cell line. The TWAJ Human/Mouse Gata-3 antibody will recognize both forms (50 and 45 kDa) of the protein.
Features
- Excitation: 488-561 nm; Emission: 578 nm; Laser: Blue Laser, Green Laser, Yellow-Green Laser.
- Filtration: 0.2 µm post-manufacturing filtered.
There are no specifications
There are no report
You May Also Like
Invitrogen EOMES Monoclonal Antibody (Dan11mag), eFluor 450, 100 µg, eBioscience™
$ On demand
On demand
Invitrogen 50 µg CD45R (B220) Monoclonal Antibody (RA3-6B2), Biotin, eBioscience™
$ On demand
On demand
Invitrogen TLR4/MD-2 Complex Monoclonal Antibody (MTS510), PE, 100 µg, eBioscience™
$ On demand
On demand
Invitrogen 25 µg Rat IgG2b kappa Isotype Control (eB149/10H5), Super Bright 436, eBioscience™
$ On demand
On demand
Invitrogen Armenian Hamster IgG Isotype Control (eBio299Arm), Alexa Fluor 700, 25 µg, eBioscience™
$ On demand
On demand
Invitrogen Mouse IgG2a kappa Isotype Control (eBM2a), Alexa Fluor™ 660, 50 µg, eBioscience™
$ 280
On demand
Invitrogen 100 µg CD140b (PDGFRB) Monoclonal Antibody (APB5), PE-eFluor 610, eBioscience™
$ On demand