Invitrogen IL-22 Monoclonal Antibody (IL22JOP), Functional Grade, 5 mg, eBioscience™
On demandInvitrogen IL-22 Monoclonal Antibody (IL22JOP), Functional Grade, 5 mg, eBioscience™
The monoclonal antibody IL22JOP reacts with and inhibits the bioactivity of human and mouse IL-22. IL-22 is a 20 kDa member of the IL-10 cytokine family that is secreted primarily by Th17 cells, NK cells, and other T cells. Compared to IL-6 or TGF beta, IL-23 can induce greater levels of IL-22 in in vitro-differentiated Th17 cells. This observation suggests that IL-22 may be secreted by more fully differentiated Th17 cells in vivo. Recently, it was demonstrated that IL-22 could protect hosts from bacterial infection of the lungs and gut. Moreover, it has been reported that anti-CD3/CD28-induced production of IL-22 by PBMCs was elevated significantly in asthma patients compared to control patients. Flow cytometric analysis also showed that the frequencies of IL-17+IL-22+ CD4 T cells were increased in PBMCs from patients with ankylosing spondylitis and rheumatoid arthritis.
Features
- Storage and handling: Use in a sterile environment.
- Filtration: 0.2 µm post-manufacturing filtered.
- Purity: Greater than 90%, as determined by SDS-PAGE.
- Endotoxin Level: Less than 0.001 ng/µg antibody, as determined by LAL assay.
- Aggregation: Less than 10%, as determined by HPLC.
- Applications: Neutralization (Neu), Functional Assay (FN).
- Recommended Isotype Control: Rat IgG2a kappa Isotype Control (eBR2a), Functional Grade, eBioscience™.
There are no specifications
There are no report
You May Also Like
![](https://laboshop.ae/public/storage/files/d047c802-96ac-4d16-8070-1c1129f71015.png)
Invitrogen IL-13 Monoclonal Antibody (eBio13A), Alexa Fluor 488, 100 µg, eBioscience™
$ On demand
On demand
![](https://laboshop.ae/public/storage/files/234fccf2-768b-4b10-9378-6833ba4b62eb.png)
Invitrogen CD56 (NCAM) Monoclonal Antibody (TULY56), APC, 100 Tests, eBioscience™
$ 328
On demand
![](https://laboshop.ae/public/storage/files/9c1eabe4-9775-4043-9037-c593908f058a.jpg)
Thermo Scientific™ LanthaScreen™ Tb-p-c-jun (pSer73) Antibody Kit, 1 mg
$ 21
On demand
![](https://laboshop.ae/public/storage/files/dcc564df-e4ef-444f-a676-cad30fd4662c.png)
Invitrogen CD16 Monoclonal Antibody (eBioCB16 (CB16)), APC-eFluor™ 780, 100 Tests, eBioscience™
$ On demand
On demand
![](https://laboshop.ae/public/storage/files/1acf5ef2-2ce6-4a91-9af2-77488d07ecf6.png)
Invitrogen CD4 Monoclonal Antibody (SK3 (SK-3)), NovaFluor Blue 610-30S, 100 Tests, eBioscience™
$ On demand
On demand
![](https://laboshop.ae/public/storage/files/8dd37864-350a-4971-a47c-6f5b60029e02.png)
Invitrogen HLA-DR Monoclonal Antibody (LN3), Alexa Fluor 660, 100 Tests, eBioscience™
$ On demand
On demand
![](https://laboshop.ae/public/storage/files/a33fb0dc-b038-4a61-b4f3-b04909b0799a.png)
Invitrogen CD40 Monoclonal Antibody (1C10), PE, 200 µg, eBioscience™
$ On demand
On demand
![](https://laboshop.ae/public/storage/files/113eb0e7-e716-4674-9875-de5e56d7543b.png)
Invitrogen CD90.2 (Thy-1.2) Monoclonal Antibody (53-2.1), APC, 50 µg, eBioscience™
$ 193