Invitrogen IL-22 Monoclonal Antibody (IL22JOP), Functional Grade, 500 µg, eBioscience™
On demandInvitrogen IL-22 Monoclonal Antibody (IL22JOP), Functional Grade, 500 µg, eBioscience™
The monoclonal antibody IL22JOP reacts with and inhibits the bioactivity of human and mouse IL-22. IL-22 is a 20 kDa member of the IL-10 cytokine family that is secreted primarily by Th17 cells, NK cells, and other T cells. Compared to IL-6 or TGF beta, IL-23 can induce greater levels of IL-22 in in vitro-differentiated Th17 cells. This observation suggests that IL-22 may be secreted by more fully differentiated Th17 cells in vivo. Recently, it was demonstrated that IL-22 could protect hosts from bacterial infection of the lungs and gut. Moreover, it has been reported that anti-CD3/CD28-induced production of IL-22 by PBMCs was elevated significantly in asthma patients compared to control patients. Flow cytometric analysis also showed that the frequencies of IL-17+IL-22+ CD4 T cells were increased in PBMCs from patients with ankylosing spondylitis and rheumatoid arthritis.
Features
- Storage and handling: Use in a sterile environment.
- Filtration: 0.2 µm post-manufacturing filtered.
- Purity: Greater than 90%, as determined by SDS-PAGE.
- Endotoxin Level: Less than 0.001 ng/µg antibody, as determined by LAL assay.
- Aggregation: Less than 10%, as determined by HPLC.
- Applications: Neutralization (Neu), Functional Assay (FN).
- Recommended Isotype Control: Rat IgG2a kappa Isotype Control (eBR2a), Functional Grade, eBioscience™.
There are no specifications
There are no report
You May Also Like
![](https://laboshop.ae/public/storage/files/97ad064c-a396-4566-bcd6-0ce089d1ee40.png)
Invitrogen beta Actin Monoclonal Antibody (15G5A11/E2), Alexa Fluor 488
$ On demand
On demand
![](https://laboshop.ae/public/storage/files/33992ee5-f0a9-4ccd-86d5-7dfc2707edfd.png)
Invitrogen 100 µg Rat IgG2b kappa Isotype Control (eB149/10H5), Super Bright 600, eBioscience™
$ On demand
On demand
![](https://laboshop.ae/public/storage/files/635a9469-1c51-4ae7-8284-be8d6f35faf2.png)
Invitrogen 100 µg CD45R (B220) Monoclonal Antibody (RA3-6B2), Alexa Fluor 561, eBioscience™
$ On demand
On demand
![](https://laboshop.ae/public/storage/files/5042e56b-c0a9-4225-9609-d9acc871a95c.png)
Invitrogen CD11c Monoclonal Antibody (N418), NovaFluor Blue 510, 25 µg, eBioscience™
$ On demand
On demand
![](https://laboshop.ae/public/storage/files/8ec853a3-c06f-47d7-8f8d-e16807cd11ef.png)
Invitrogen 100 µg CD140b (PDGFRB) Monoclonal Antibody (APB5), PE-Cyanine7, eBioscience™
$ On demand
On demand
![](https://laboshop.ae/public/storage/files/59640377-c9fb-41d1-911d-407860993a92.png)
Invitrogen GL7 Monoclonal Antibody (GL-7 (GL7)), PerCP-eFluor™ 710, 25 µg, eBioscience™
$ On demand
On demand
![](https://laboshop.ae/public/storage/files/947c8331-f337-4c1b-8a21-9eb95317d23d.png)
Invitrogen Armenian Hamster IgG Isotype Control (eBio299Arm), Functional Grade, 5 mg, eBioscience™
$ On demand