Invitrogen™ LentiArray™ Human Cell Cycle CRISPR Library, Glycerol

Invitrogen™ LentiArray™ Human Cell Cycle CRISPR Library, Glycerol

The award-winning Invitrogen™ LentiArray™ Human Cell Cycle Library targets 1,444 genes with up to 4 gRNA per gene target for a total of 5,776 gRNAs. Libraries are delivered as 50 μL of glycerol stock per gRNA and are also available as ready to use packaged lentivirus.

Cell cycle regulators are important to normal development and also play a role in the development of cancer, cardiovascular, inflammatory, and neurodegenerative diseases. The gene targets within the LentiArray Human Cell Cycle Library were selected using the most up-to-date genome databases, including the NCBI RefSeq database, and cross-referenced to the Gene Ontology Consortium (GO) database and/or the HUGO Gene Nomenclature Committee (HGNC), and include cyclin-dependent kinases, or CDKs, regulators of cell cycle progression such as CIP/KIP family proteins and members of the INK4 family of cell cycle inhibitors, proteins in the retinoblastoma family, and DNA replication factors such as the cell division cycle proteins (CDCs). The gRNA designs for each target were created using Thermo Fisher Scientific's proprietary gRNA design algorithm.

Contents

• 1 library set, 50 µL/target