Invitrogen™ Silencer™ Human Drug Transporter siRNA Library

Invitrogen™ Silencer™ Human Drug Transporter siRNA Library

Transporter proteins play a key role in pharmacology, affecting how molecules are moved across cellular membranes. The Silencer™ Human Drug Transporter siRNA Library includes genes important to the absorption, distribution, metabolism and excretion of many drugs. The Silencer Human Drug Transporter siRNA Library contains 297 Ambion™ Silencer siRNAs targeting 99 genes for performing RNAi screens against drug transporters. The library was designed using the most up-to-date genome databases, including the NCBI RefSeq database and cross-referenced to the Gene Ontology Consortium (GO) database and/or the HUGO Gene Nomenclature Committee (HGNC). Utilizing Ambion Silencer technology built on stringent bioinformatics to enable high target specificity and siRNA potency, the Silencer Human Drug Transporter siRNA Library is an ideal solution for focused and cost-effective RNAi screens against pharmaceutical drug transporter proteins.

Features

• Comprehensive—Expedite functional gene discovery with pre-defined Silencer Human GPCR siRNA Library
• Reliable—Increase target screening accuracy with three individual siRNAs per gene target
• Effective—Reduce off target impacts at low concentrations with proven Ambion Silencer siRNA design
• Convenient—Reduce data de-convolution and accelerate target validation with our arrayed format
• Customizable—Choose the best option for your workflow demands, including additional siRNA scales and pooled formats

Contents

• 297 total siRNAs targeting 99 genes plated onto 96-well plates (6 plates)