Invitrogen PCNA Monoclonal Antibody (PC10), Biotin, 100 µg
On demandInvitrogen PCNA Monoclonal Antibody (PC10), Biotin, 100 µg
PCNA (polymerase delta auxiliary protein) is essential for DNA replication and is involved in DNA excision and mismatch repair pathways. PCNA binds to the CDK inhibitor p21, the structure-specific endonucleases Fen1 and XPG, and DNA cytosine 5-methyltransferase (MCMT). PCNA is a potentially useful marker of cells with proliferative potential and for identifying the proliferation status of tumor tissue (i.e. relevant to prognosis). PCNA is a marker for cells in early G1 phase and S phase of the cell cycle. PCNA is found in the nucleus and is a cofactor of DNA polymerase delta, and acts as a homotrimer and helps increase the processing of leading strand synthesis during DNA replication. In response to DNA damage, PCNA is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for PCNA. Pseudogenes of PCNA have been described on chromosome 4 and on the X chromosome.
MoreThere are no specifications
There are no report
You May Also Like
Invitrogen Rat IgM Isotype Control (eBRM), eFluor™ 660, 25 µg, eBioscience™
$ On demand
On demand
Invitrogen IL-13 Monoclonal Antibody (eBio13A), PE, 100 µg, eBioscience™
$ On demand
On demand
Invitrogen CD45 Monoclonal Antibody (30-F11), Functional Grade, 50 mg, eBioscience™
$ On demand
On demand
Invitrogen IL-1 beta (Pro-form) Monoclonal Antibody (NJTEN3), PE-Cyanine7, 100 µg, eBioscience™
$ On demand
On demand
Invitrogen Mouse IgG1 kappa Isotype Control (P3.6.2.8.1), APC-eFluor 780, 25 µg, eBioscience™
$ On demand
On demand
Invitrogen 25 µg Ly-6G/Ly-6C Monoclonal Antibody (RB6-8C5), PE-Cyanine5.5, eBioscience™
$ On demand
On demand
Invitrogen HLA-DR Monoclonal Antibody (LN3), FITC, 25 Tests, eBioscience™
$ On demand
On demand
Invitrogen SOX11 Monoclonal Antibody (SOX11-C1), eFluor 660, 25 µg, eBioscience™
$ On demand