Invitrogen™ Silencer™ Select Human Long Non-coding RNA (lncRNA) siRNA Library (96 well)

Invitrogen™ Silencer™ Select Human Long Non-coding RNA (lncRNA) siRNA Library (96 well)

Long noncoding RNAs (lncRNAs) have gained interest in recent years as they have been implicated in genomic regulation, cellular housekeeping functions, developmental processes and disease. The Silencer™ Select Human Long Noncoding RNA (lncRNA) siRNA Library contains 15,081 Ambion™ Silencer Select siRNAs targeting 5,027 lncRNAs as identified in GENCODE v22. The Silencer Select Human Long Noncoding RNA (lncRNA) siRNA Library is designed against targeted transcripts aligned to the entire genome, maximizing prediction and coverage across alternatively spliced transcripts. Silencer Select siRNAs are designed with Thermo Fisher Scientific’s leading design algorithms and locked nucleic acid (LNA) chemical modifications to help ensure efficacy, specificity and potency. This in turn provides a powerful platform for achieving accurate and consistent phenotype data from RNAi screens in the discovery and elucidation of lncRNAs.

Features

• Superior efficacy—Reduce off target effects by up to 90% due to latest design algorithms and LNA chemical modifications
• Highest efficiency—Perform knockdown studies with 100-fold more potent siRNAs than currently available siRNAs
• Dependable—Achieve faster discoveries via consistency of gene knockdown and reliability of phenotypic results
• Convenient—Reduce data de-convolution and accelerate target validation with our arrayed format
• Customizable—Choose the best option for your workflow demands, including additional siRNA scales and pooled formats

Contents

• 15081 total siRNAs targeting 5027 lncRNA transcripts plated onto 96-well plates (174 plates)