TEL-AML1, (FISH)
On demand
Order number :
HE-F19
t(12;21) Translocation
Main indication:
ALL
Test usage:
The TEL/AML1 is a gene fusion resulting from a t(12;21)(p13;q22) chromosomal translocation, it is the most common genetic rearrangement in B-lineage pediatric ALL (frequency ~25%). the TEL/AML1 gene fusion is associated with a more favorable prognosis as evidenced by a significantly lower relapse rate. Relapse is associated with reappearance of the transcript; thus testing is useful for monitoring patients for current disease status.
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