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TEL-AML1, (FISH)

On demand
Order number : HE-F19
(Ex-work price)
$ On demand

t(12;21) Translocation


Main indication:

ALL


Test usage:

The TEL/AML1 is a gene fusion resulting from a t(12;21)(p13;q22) chromosomal translocation, it is the most common genetic rearrangement in B-lineage pediatric ALL (frequency ~25%). the TEL/AML1 gene fusion is associated with a more favorable prognosis as evidenced by a significantly lower relapse rate. Relapse is associated with reappearance of the transcript; thus testing is useful for monitoring patients for current disease status.

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