Thermo Scientific™ CaptureSelect™ Biotin Anti-LC-lambda (Human) Conjugate, 500 µg

Thermo Scientific™ CaptureSelect™ Biotin Anti-LC-lambda (Human) Conjugate, 500 µg

CaptureSelect™ Biotin Anti-LC-lambda (Hu) Conjugate consists of a 13 kDa llama antibody fragment (affinity ligand) that specifically binds to the constant domain of human lambda light chains. The affinity ligand is chemically conjugated to biotin via an appropriate spacer that retains the binding reactivity of the ligand when used in combination with streptavidin-based conjugates or streptavidin pre-coated surfaces.

Features

• Detect, quantitate, and characterize all human antibody isotypes and subclasses (for example, IgG1 to 4, IgM, IgA, IgD, and IgE), and Fab fragments thereof, that contain a lambda light chain; as well as recombinant human Fab fragments and/or Fab and Fab2 fragments obtained after papain or pepsin digestion
• Avoid cross-binding with human antibodies that possess a kappa light chain or IgG from, for example, mouse, rat, or rabbit
• Screen antibody-antigen interactions — biotin anti-LC-lambda (Hu) forms a stable [low k(diss)] complex with, for example, human IgG antibodies through bivalent binding