Thermo Scientific™ CaptureSelect™ CH1-XL Ligand Leakage ELISA, 1 Assay
On demandThermo Scientific™ CaptureSelect™ CH1-XL Ligand Leakage ELISA, 1 Assay
The CaptureSelect CH1-XL Ligand Leakage ELISA Kit detects affinity ligand contamination of antibodies or antibody fragments purified using CaptureSelect CH1-XL Affinity Matrix. The ligand, a 14-kD recombinant protein, is covalently coupled for high chemical stability and low leakage. Even when covalently attached, small amounts of the affinity ligand can leach off of the chromatography support and co-elute with the protein. This sensitive ELISA detects affinity ligand contamination of less than 1 ng/mL. The assay is designed to minimize interference and to provide accurate quantitation even in the presence of the protein of interest. The CaptureSelect CH1-XL Ligand Leakage ELISA Kit can be used as a tool to aid in development of an optimal purification process and in routine quality control of in-process streams and final product.
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