Thermo Scientific™ CaptureSelect™ Prothrombin Affinity Matrix, 5 mL

Thermo Scientific™ CaptureSelect™ Prothrombin Affinity Matrix, 5 mL

CaptureSelect Prothrombin Affinity Matrix has been specifically designed for the purification of human prothrombin (coagulation Factor II). This matrix binds both native and recombinant human prothrombin.

Prothrombin is a vitamin-K dependent plasma protein which is produced in the liver. The presence of calcium promotes the binding of prothrombin to phospholipid bilayers.

Features

• Highly selective for human prothrombin without cross reactivity to other human plasma proteins
• Binds different forms of prothrombin (Factor II and Factor IIa) in the presence of calcium
• Enables efficient purification of prothrombin with high yields and retained activity
• Mild elution at neutral pH using EDTA
• Excellent scalability
• Non-animal-derived