Thermo Scientific™ CaptureSelect™ Prothrombin Affinity Matrix, 50 mL

Thermo Scientific™ CaptureSelect™ Prothrombin Affinity Matrix, 50 mL

CaptureSelect Prothrombin Affinity Matrix has been specifically designed for the purification of human prothrombin (coagulation Factor II). This matrix binds both native and recombinant human prothrombin.

Prothrombin is a vitamin-K dependent plasma protein which is produced in the liver. The presence of calcium promotes the binding of prothrombin to phospholipid bilayers.

Features

• Highly selective for human prothrombin without cross reactivity to other human plasma proteins
• Binds different forms of prothrombin (Factor II and Factor IIa) in the presence of calcium
• Enables efficient purification of prothrombin with high yields and retained activity
• Mild elution at neutral pH using EDTA
• Excellent scalability
• Non-animal-derived