Thermo Scientific™ MabCaptureC™ Affinity Matrix, 1 L

Thermo Scientific™ MabCaptureC™ Affinity Matrix, 1 L

MabCaptureC Affinity Matrix is an agarose-based, high-binding-capacity Protein A chromatography resin with a rProtein A ligand produced in yeast. The engineered rProtein A binds at the CH2-CH3 interface of the Fc-region of IgGs and shows cross binding to the VH3 domain of IgGs. MabCaptureC Affinity Matrix is suitable for the purification of monoclonal antibodies.The rProtein A ligand is immobilized on a highly cross-linked and uniform-sized agarose-based bead with an average particle size of 75 µm. The uniform particle size delivers superior performance characteristics compared to traditional Protein A resins.

Features

• High dynamic binding capacity for mAbs of >50 g/L at 4.8 min residence time
• Purification of mAbs and a subpopulation of scFv’s and Fab fragments containing VH3 binding domains
• Clean and sanitize with standard sodium hydroxide agents for chromatography products
• Excellent scalability
• Non-animal derived