Thermo Scientific™ Pierce™ Chymotrypsin Protease (TLCK treated), MS Grade

Thermo Scientific™ Pierce™ Chymotrypsin Protease (TLCK treated), MS Grade

Thermo Scientific Chymotrypsin Protease, MS Grade, is a purified native endoproteinase validated for maximum activity and selectivity in proteomic applications.

This Chymotrypsin is a mass spectrometry (MS)-grade serine protease isolated from bovine pancreatic extracts. This chymotrypsin is TLCK-treated to eliminate tryptic activity. The selectivity of this enzyme is important for reproducible protein digestion and mass spectrometry-based protein identification. Chymotrypsin-digestion typically generates a larger number of shorter peptides compared to trypsin. This mass spectrometry-grade Chymotrypsin is packaged lyophilized (convenient 4 x 25 µg).

Features

• Increased sequence coverage—cleaves at the carboxyl side of tyrosine, phenylalanine, tryptophan and leucine
• Better specificity—treated with TLCK to eliminate trypsin activity
• High activity—greater than 45 units/mg protein