Thermo Scientific™ Pierce™ Iodoacetic Acid
On demand
Order number :
35603
Thermo Scientific™ Pierce™ Iodoacetic Acid
Thermo Scientific Pierce Iodoacetic Acid (IAA) can react with several protein functional groups but is typically used for specific S-carboxymethylation of sulfhydryls (reduced cysteines).
Features
- React at slightly alkaline pH for specific S-carboxymethylation of free sulfhydryls
- React at low pH for specific carboxymethylation of methionines
- React at high pH to favor carboxymethylation of histidines and lysines
- Methylate reduced cysteine peptide fragments in protease digests for mass spectrometry
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